Alexander MP et al., Brain 2003.
CVLT has many measures.
Immediate free recall-- posterior LDF (dorsolateral frontal) performed worse, than other frontal areas
List A first trial-- posterior LDF and PMF (posterior medial frontal) were most impaired
Trial by groups-- left LDF had flattest learning curve.
Primacy/recency and serial position had no effects by group.
List B-- proactive interference was not present in any group
Recognition memory-- posterior LDF group and posterior RDF group performed worst. Recognition hits were not different, difference was due to more false alarms.
Discriminibility and response bias-- the post LDF performed worse than all except post RDF.
Short delayed free recall-- post LDF was worse than controls. Ant RDF & PMF were different than controls.
Long delay free recall-- post LDF worse than all groups except ant LDF & PMF.
Long delay cued recall similar to above.
Intrusions and double recalls-- no significant differences.
Inconsistency score-- post LDF was worse than all except post RDF
Subjective semantic organization-- RDF post worse.
Summary-- Immediate free recall was worse post LDF> PMF (esp bilateral involving septal area)> post RDF. This was also true for delayed free recall short and long, and for learning curve for trial 1-5. For recognition only LDF was impaired due to more false alarms.
In a prior study, Stuss et al. found more double recalls in post. RDF group, not seen in this study although p=0.11. Abnormalities cannot be attributed to PI, to serial position effect, or defective primary memory.
Monday, July 26, 2010
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